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Search Results for " syk in 1 "

9

Compounds

Cat No. Product Name Synonyms Targets
T24843 Syk-IN-1 SykIN11,Syk-IN-11,Syk IN 11,Syk inhibitor-11,Syk inhibitor 11,Syk-inhibitor-11
Syk-IN-11 is a selective Syk inhibitor.
T63086 SYK/JAK-IN-1
SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.
T9543 Syk Inhibitor II hydrochloride Others
The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of...
T4S0498 Glaucocalyxin A Wangzaozin B,Leukamenin F Apoptosis , Akt , Caspase , PI3K
1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...
T3211 Midostaurin N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251 Others , PKC
PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel...
T78943 Syk-IN-7 Syk
Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].
T37077 Syk-IN-4
Syk-IN-4 is a potent, selective, and orally bioavailable inhibitor of SYK, demonstrating an IC50 of 0.31 nM. It targets SYK, which has been identified as a potential therapeutic target for autoimmunity and hematological ...
T79443 Syk-IN-8 Syk
Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells. It specifically inhibits PLCγ2 phosphorylation and is applicable for blood cance...
T61527 GSK2646264
GSK2646264 (Compound 44) is a highly effective and specific inhibitor of spleen tyrosine kinase (SYK) with a pIC50 of 7.1. In addition to targeting SYK, GSK2646264 also inhibits several other kinases, including LCK, LRRK...
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